It is primarily used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Benefits:
-Reduces intraocular pressure effectively, helping to prevent damage to the optic nerve.
-Combines two mechanisms of action for enhanced efficacy compared to single-agent therapies.
-Convenient formulation as a topical eye drop, allowing for direct application to the eye.
Precautions:
-Not recommended for individuals with a known hypersensitivity to any component of the formulation.
-Caution is advised in patients with respiratory conditions such as asthma or chronic obstructive pulmonary disease (COPD) due to the beta-blocker component.
-Patients with heart conditions should consult their healthcare provider before use.
-Use during pregnancy and breastfeeding should be discussed with a healthcare professional.
Side Effects:
-Common side effects may include burning or stinging upon instillation, blurred vision, and dry eyes.
-Serious side effects can include allergic reactions, difficulty breathing, slow heart rate, or worsening of respiratory conditions.
-Long-term use may lead to systemic absorption of timolol, potentially causing cardiovascular or respiratory issues.
Main Ingredients and Their Benefits:
-Brinzolamide (10 mg)
Brinzolamide is a carbonic anhydrase inhibitor that reduces intraocular pressure (IOP) by decreasing the production of aqueous humor in the eye, which is beneficial for patients with open-angle glaucoma or ocular hypertension.
-Timolol (5 mg)
Timolol is a non-selective beta-adrenergic antagonist that also lowers IOP by reducing aqueous humor production and increasing outflow, making it effective in managing elevated IOP associated with glaucoma.
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