Entresto 100 mg contains Sacubitril (49 mg) and Valsartan (51 mg) in film-coated tablets, classified under heart failure drugs. This medicine is a first-in-class angiotensin receptor-neprilysin inhibitor that works by simultaneously inhibiting vasoconstriction and promoting vasodilation, leading to relaxed blood vessels, improved blood flow, and reduced stress on the heart.

Benefits:
- Treats long-term heart failure in adults.
- Alleviates symptoms such as breathlessness, fatigue, tiredness, and ankle swelling.
- Improves heart function and quality of life.

Precautions:
- Do not take if allergic to Sacubitril, Valsartan, or any other components.
- Avoid if currently using an ACE inhibitor; wait 36 hours after the last dose before starting this medication.
- Not recommended for individuals with severe liver disease, or those who are more than 3 months pregnant.
- Consult a doctor if experiencing low blood pressure, kidney disease, or dehydration.

Side Effects:
- Possible low blood pressure (dizziness, light-headedness).
- Elevated potassium levels in blood (detectable by blood tests).
- Decreased kidney function.
- Other effects may include cough, dizziness, or diarrhea.

Main Ingredients & Their Benefits:
- Sacubitril: Enhances natriuretic peptide levels, promoting vasodilation and reducing fluid overload.
- Valsartan: An angiotensin receptor blocker that helps lower blood pressure and reduce strain on the heart.