Scientific Name Naproxen 250 Mg Tablets Mechanism Of Action Of Naproxen The main mechanism of action of NSAIDs is the inhibition of the enzyme cyclooxygenase (COX). Cyclooxygenase is required to convert arachidonic acid into thromboxanes, prostaglandins, and prostacyclins. The body releases these substances in response to illness and injury. Naproxen reduces pain, fever, swelling, and inflammation Therapeutic Indications Of Proxen 250 Mg Tablets Diseases of joints such as rheumatoid arthritis (including in children), osteoarthritis, ankylosing spondylitis. Naproxen cannot cure arthritis but is used to give relief of some symptoms such as inflammation, swelling, stiffness, and joint pain Attacks of gout Muscle and bone disorders Painful periods Method Of Administration Of Proxen 250 Mg Tablets Take as prescribed Swallow with or after food Adults: Rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: 500mg-1g a day in two doses at twelve-hour intervals. Attack of gout: Initially 750mg as a single dose then 250mg every 8 hours until the attack has passed. Muscle, bone disorders, and painful periods: Initially 500mg as a single dose then 250mg every 6-8 hours as necessary. Use in children and adolescents Children over 5 years for juvenile rheumatoid arthritis: 10mg per kg of body weight a day Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions. If you take more than you should, talk to a doctor or go to the hospital straight away. If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose. Do not take a double dose (two doses at the same time) to make up for the forgotten dose. Undesirable Side Effects Of Proxen 250 Mg Tablets Common side effects: Headache Dizziness Tiredness Stop taking Naproxen if: You have indigestion, heartburn, pains in your stomach or other abnormal stomach symptoms, feeling or being sick, diarrhea, worsening of colitis, and Crohn’s disease (you may have an ulcer or inflammation in the stomach or gut) You pass blood in your feces (stools/motions) or black tarry looking stools (signs of bleeding and perforation of the stomach and intestines) You vomit any blood or dark particles that look like coffee grounds You have an allergic reaction: swelling of the face, difficulty breathing Pregnancy & Breastfeeding Precautions While Taking Proxen 250 Mg Tablets If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Non-Pharmacological Treatments & Advice To Reduce Pain Massage: A lot of people find relief from gentle massage, and some hospice agencies have volunteers who are trained in massage therapy. Acupuncture. Physical therapy Gel packs.