A vaginal antifungal medication used to treat vaginal yeast infections and fungal-related inflammation by inhibiting ergosterol synthesis in fungal cell membranes, leading to disruption of fungal growth and cell death.
Indications:
- Vaginal discharge caused by fungi (mainly Candida).
- Vaginal inflammation due to fungal infections.
- Mixed or superinfections involving clotrimazole-sensitive bacteria.
Main Active Ingredient:
- Clotrimazole 200 mg per vaginal tablet.
Precautions:
- Do not use if allergic to clotrimazole or any excipients.
- Use with caution in the first trimester of pregnancy; avoid applicator use during pregnancy.
- Avoid treatment during menstruation.
- Inform your doctor of concurrent medications (e.g., amphotericin, nystatin, dexamethasone).
- Keep out of reach of children.
- Do not store above 30 °C.
- Do not use after the expiry date on the carton/blister.
Side Effects:
- Occasionally: Vaginal burning, stinging, mild skin reactions (redness, rash, itching).
- Rarely: Blisters, peeling, edema, contact allergy.
- Very rarely: Abdominal cramps, increased urination.
Drug–Drug Interactions:
- May reduce effectiveness of amphotericin and other polyene antifungals (nystatin, natamycin).
- High doses of dexamethasone may reduce clotrimazole efficacy.
- Insert one vaginal tablet deeply into the vagina at bedtime, once daily, for 3 consecutive days, or as directed by a healthcare professional.
- Wash hands thoroughly before and after application.
- If provided, use the applicator for insertion unless pregnant (in pregnancy, insert the tablet manually without applicator).
- Complete the full course of treatment even if symptoms improve earlier.
- Avoid sexual intercourse during treatment, as the infection may transmit and symptoms may worsen.
Clotrimazole, Lactose Monohydrate, Corn Starch, Polysorbate 80, Magnesium Stearate, Sodium Hydrogen Carbonate, Adipic Acid, Stearic Acid, Highly Dispersed Silicon Dioxide.
Clotrimazole
