An extended-release oral antidiabetic medication used in the management of type 2 diabetes mellitus. It helps control blood glucose levels by reducing hepatic glucose production, decreasing intestinal absorption of glucose, and improving insulin sensitivity.Indications:- Management of type 2 diabetes mellitus (non-insulin-dependent diabetes).- Can be used as monotherapy when diet and exercise alone are insufficient.- May be used in combination with other antidiabetic agents (e.g., sulfonylureas, DPP-4 inhibitors, insulin) when - - additional glycemic control is required.- Helps reduce the risk of diabetes-related complications when blood sugar is controlled.Main Active Ingredient::- Metformin Hydrochloride (Extended Release) 750 mg per tablet.Precautions:- For oral use only.- Contraindicated in patients with:- Severe renal impairment (eGFR < 30 mL/min/1.73m²).- Acute or chronic metabolic acidosis (including diabetic ketoacidosis).- Severe liver disease or alcoholism.Use with caution in:- Elderly patients.- Those with heart failure, hypoxia, or dehydration.- Patients undergoing surgery or radiological procedures with iodinated contrast (risk of lactic acidosis).- Avoid excessive alcohol intake as it increases the risk of lactic acidosis.- Regular monitoring of kidney and liver function is advised.- Not recommended during pregnancy or breastfeeding unless prescribed.Side Effects:- Nausea.- Vomiting.- Diarrhea.- Abdominal pain.- loss of appetite.- Taste disturbances.- Headache.- Mild weight loss.- Lactic acidosis.- Long-term use May reduce vitamin B12 absorption, leading to deficiency.Drug–Drug Interactions:- Iodinated contrast media.- Alcohol.- Cimetidine and other drugs affecting renal clearance.- Diuretics.- Certain antihypertensives (ACE inhibitors, ARBs).

- Usual starting dose: One tablet (750 mg) once daily with the evening meal.- Tablets must be swallowed whole with water; do not crush or chew.- Dose may be adjusted by a physician depending on blood glucose response, up to a maximum of 2250 mg once daily.- Take with food to minimize gastrointestinal side effects.- If a dose is missed, take it as soon as remembered unless it’s - - near the next dose (do not double dose).Regular blood glucose monitoring is recommended.

• Anti-diabetic

metformin hydrochloride