It is primarily used to improve glycemic control in adults with type 2 diabetes mellitus.
The combination works by reducing glucose production in the liver, increasing insulin sensitivity, and promoting the excretion of glucose through urine.
Benefits:
-Helps lower blood sugar levels effectively when used alongside diet and exercise.
-Reduces the risk of cardiovascular events in patients with type 2 diabetes who have established cardiovascular disease.
-May aid in weight loss or weight maintenance compared to other diabetes medications.
-Can be taken once daily, improving adherence to treatment.
Precautions:
-Not suitable for individuals with severe renal impairment or end-stage renal disease.
-Caution is advised for patients with a history of pancreatitis or those who consume excessive alcohol.
-Regular monitoring of kidney function is necessary during treatment.
-Patients should inform their healthcare provider about any other medications they are taking to avoid potential interactions.
Side Effects:
-Common side effects may include gastrointestinal issues such as nausea, vomiting, diarrhea, and abdominal pain.
-Risk of urinary tract infections (UTIs) due to increased glucose in urine.
-Rare but serious side effects include lactic acidosis, which can occur if metformin accumulates in the body.
-Hypoglycemia may occur when combined with other antidiabetic agents.
Main Ingredients & Their Benefits:
-Empagliflozin: This medication falls under the category of sodium-glucose co-transporter-2 (SGLT2) inhibitors. It works by blocking the SGLT2 protein in the kidneys, leading to the excretion of glucose through urine.
-Metformin: It reduces blood sugar levels primarily by inhibiting glucose production in the liver.
Contraindications:
-Do not use this medication if you:
-Are allergic to empagliflozin, metformin, or any components of the formulation.
-Have poorly controlled diabetes, severe hyperglycemia, nausea, vomiting, diarrhea, rapid weight loss, lactic acidosis, or ketoacidosis.
-Suffer from severely impaired kidney function.
-Have a severe infection (especially in the lungs, airways, or kidneys).
-Are dehydrated due to prolonged vomiting or diarrhea.
-Are treated for severe heart failure or have recently experienced a heart attack.
-Have liver issues.
-Consume excessive amounts of alcohol.
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